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Image Search Results
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Article Title: Quercetin alleviates cadmium chloride-induced renal damage in rats by suppressing endoplasmic reticulum stress through SIRT1-dependent deacetylation of Xbp-1s and eIF2α.
doi: 10.1016/j.biopha.2021.111862
Figure Lengend Snippet: Fig. 6. Assessment of Bax, caspase-3, and Bcl2, ratio of Bax/Bcl2, and total protein expression of cleaved caspase-3. Total levels of Bax (A), caspase-3 (B), and Bcl2 (C), ratio of Bax/Bcl2 (D), as well as the total protein expression of cleaved caspase-3 (E) in the kidneys of all rats. In E: the left panel indicates the western blot and the right panel presents the quantification of caspase-3. Data are presented as mean ± SD and analysed by one-way ANOVA followed by Tukey’s t-test as a post-hoc test. For the biochemical data, all parameters were measured in duplicate; n = 8/group. For western blotting, data were analysed for n = 6 samples/group. a: vs. control rats (lanes 1, 2); b: vs. control + QUR-treated rats (lanes 3, 4); c:vs. CdCl2-treated rats (lanes 5, 6); d:vs. CdCl2 + QUR-treated rats (lanes 7, 8). Lane 9 represents CdCl2 + QUR + EX-527-treated rats. EX-527: SIRT1 inhibitor.
Article Snippet: Hepatic levels of caspase-3 (Casp-3) (0.23–20 ng/mL), Bax (60–4000 pg/mL), and
Techniques: Expressing, Western Blot, Control